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Early Genital Herpes Treatment Increases Your Natural Viral Suppression

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Treating genital herpes soon as possible upon diagnosis, rather than waiting for a breakout patterns to emerge, equates to  better suppression of the virus, a study of 384 patients found. Nearly 71% of newly diagnosed patients who were given valacyclovir for 24 weeks were recurrence-free, compared with 43% who were given a placebo.

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Genital herpes therapy effective if begun early

HerpesLifeLine
Wed Jul 16, 2008 6:43pm BST

NEW YORK (Reuters Health) – Treatment to suppress outbreaks of genital herpes simplex virus type 2 (HSV-2) infection is typically begun once a recurrence pattern is established, but new research suggests that treatment started shortly after diagnosis can better suppress recurrent outbreaks.

The findings, which appear in the current issue of Sexually Transmitted Diseases, are based on a study of 384 patients with newly diagnosed genital herpes infection who were randomly assigned receive valacyclovir, also known by the trade name Valtrex, at 1 gram per day, or placebo for 24 weeks. Self-reported outbreaks were confirmed at clinic follow-up visits.

Valacyclovir was effective in preventing disease recurrences, Dr. Kenneth H. Fife, from Indiana University School of Medicine in Indianapolis, and colleagues report. After 24 weeks, 71 percent of the valacyclovir-treated subjects were recurrence-free compared with 43 percent of the placebo-treated subjects, a statistically significant difference.

Active treatment also reduced the number of monthly recurrences. On average, 0.11 monthly recurrences occurred with valacyclovir treatment, while 0.48 occurred with placebo.

Valacyclovir therapy was also well tolerated by the patients and a comparable number of adverse effects were reported by both the active-treatment and placebo groups.

Up until now, there were limited data available to guide physicians in how to treat their herpes-infected patients who had no established recurrence history, the investigators note.

They advise physicians to “consider suppressive therapy as another treatment option in newly diagnosed patients, especially in adolescents, those with difficult psychological adjustments, or those who have an uninfected partner and are concerned about transmission.”

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Sexual infections double in older people

HerpesLifeLine
By Charles Hodges


SEX ED: The number of sexually transmitted diseases has increased among the elderly.

Be careful when dating — that cougar (or that sugar daddy) could give you a sexually transmitted disease: a recent health study suggests that the rate of STDs have doubled in people over the age of 45 in the last 10 years.

The study, which appeared in June the journal Sexually Transmitted Infections, said that older people have a higher case of genital warts and herpes.

In Mecklenburg County, people ages 50 or older accounted for nearly 15 percent of new HIV cases during the last five years, according to a report from the Mecklenburg County Health Department.

The fact that older people are getting sexually transmitted disease isn’t new. In 1996, the Centers for Disease Control and Prevention reported 700 cases of infection among heterosexuals age 50 or older. Within five years, that number had doubled.

Though more older people are having sex, perhaps in part due to divorce and Viagra, there is little STD education targeted at them. Metrolina AIDS Project is known throughout the city as a place to go for free HIV testing and education, but even they don’t have a specific program targeting seniors.

“Our prevention is we target high-risk folks,” said Omar Whiteside, MAP’s director of education. And those are African-American women and men who have sex with men. “The idea is to provide programs for individuals who are most at risk and hopes that by providing those programs, you can prevent the greatest risks of new infections.”

Many seniors consider HIV a “young person’s disease,” according to the National Institute on Aging. But the Institute said that 10 percent of Americans over 50 are at risk for HIV and other STDs because they often don’t practice safe sex. Since pregnancy isn’t a concern, older sexually active people are less likely to use condoms, according to the Institute.

Sounds like a need for education.

Whiteside said the CDC has a group of programs that could be used to teach seniors about safe sex, but he doesn’t know if there is a specific program just for seniors.

Statistics from the Mecklenburg County Health Department show seniors around this area aren’t at a high risk of herpes. In a report sent to Creative Loafing showing data from 2004 and 2006, syphilis cases rose in people between the ages of 40-49 from 15 cases in 2004 to 49 cases in 2006. For people over 50, those cases rose from eight in 2004 to 19 in 2006.

Rick Christenbury, spokesman for the health department, said that genital warts isn’t a reportable disease in North Carolina.

HIV rates in seniors are low in Mecklenburg County, according to the health department’s stats. The number of new cases reported in 2004 for people between the ages of 40-49 were 111. In 2006 those cases dropped to 96. For people over 50, the number of new cases were 50 and in 2006 the new cases reported were 49.

In an e-mail, Christenbury writes: “The majority of chlamydia and gonorrhea reports are among young adults with less than two percent of reports occur among individuals 50 and over. This may reflect our screening and testing methods for these particular diseases, i.e., young adults tend to be at higher risk for chlamydia and gonorrhea and therefore are more likely to be tested.”

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